Research Library

Peer-reviewed studies supporting peptide therapies for tissue repair, recovery, and wellness.

Gastric pentadecapeptide BPC 157 in accelerating musculoskeletal soft tissue healing

Sikiric P, et al. · Current Pharmaceutical Design, 2018

Significant acceleration in tendon, ligament, and muscle healing demonstrated in animal models. BPC-157 showed consistent tissue-protective and healing effects across multiple study types.

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Emerging use of BPC-157 in orthopaedic sports medicine: A systematic review

Vasireddi N, et al. · Orthopaedic Journal of Sports Medicine, 2025

Systematic review of 36 studies (1993-2024) showing BPC-157 promotes healing by boosting growth factors and reducing inflammation in muscle, tendon, ligament, and bone injury models.

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Regenerative and protective actions of the GHK-Cu peptide in the light of new gene data

Pickart L, Margolina A. · International Journal of Molecular Sciences, 2018

Stimulates collagen synthesis and supports skin and connective tissue repair. Demonstrated systemic enhancement of healing in rats, mice, and pigs.

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GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration

Pickart L, et al. · BioMed Research International, 2015

Identified over 4,000 genes regulated by GHK, affecting tissue repair, immune function, and antioxidant responses. Demonstrated broad regenerative potential.

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Peptide Selank enhances the effect of diazepam in reducing anxiety in chronic stress conditions

Volkova A, et al. · Bulletin of Experimental Biology and Medicine, 2016

Anxiolytic effect comparable to benzodiazepines. In rats under chronic mild stress, Selank combined with diazepam almost completely eliminated stress-induced anxiety.

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Selank administration affects the expression of genes involved in GABAergic neurotransmission

Zolotarev YA, et al. · Frontiers in Pharmacology, 2016

Selank modulates GABA receptor signaling, which may explain its anxiolytic mechanism. Acts through GABAA receptors similar to benzodiazepines.

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PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation

Dalmasso G, et al. · Gastroenterology, 2008

Orally administered KPV significantly decreased inflammation in DSS and TNBS colitis mouse models. Rescued all treated animals from death during DSS colitis.

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Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of IBD

Kannengiesser K, et al. · Inflammatory Bowel Diseases, 2008

KPV reduced loss of body weight, colonic MPO activity, and markedly decreased histological signs of inflammation and pro-inflammatory cytokine levels.

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Thymosin Alpha-1Loyal Immune

Thymosin alpha 1: A comprehensive review of the literature

Costantini C, et al. · World Journal of Virology, 2020

Recognized as an immune enhancing, modulating, and restoring agent. Originally isolated for reconstitution of immune function in thymectomized animal models.

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Thymosin Alpha-1Loyal Immune

Thymosin alpha 1: Past clinical experience and future promise

Goldstein AL, Goldstein AL. · Annals of the New York Academy of Sciences, 2010

Favorable safety profile in over 2,000 individuals. Increases T cell-mediated immune responses through stimulation of T cell differentiation and NK cell activation.

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MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline

Reynolds JC, et al. · Nature Communications, 2021

Old mice (22 mo.) doubled running time after 2 weeks treatment, outperforming middle-aged mice. Significantly enhances physical performance across all age groups.

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MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation

Kim SJ, et al. · Experimental & Molecular Medicine, 2023

Prevents age-related metabolic dysfunction, insulin resistance in high-fat diet obesity, and pressure overload-induced cardiac hypertrophy in animal studies.

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